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Name:Remdesivir    

CAS NO: 1809249-37-3

Purity: 99% min

MF: C27H35N6O8P

MW:602.576

BP:N/A

Density: 1.5±0.1 g/cm3

MP: N/A

EINECS:N/A

Appearance: White powder

Package: 25g, 100g, 500g, bulk package

Application:Pharmaceutical intermediate

Other name:

(S)-2-ethylbutyl 2-(((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

What is Remdesivir  CAS NO: 1809249-37-3?

Remdesivir is a nucleoside analogue and is an RNA-dependent RNA polymerase (RdRp) inhibitor. It can synthesize by inhibiting viral nucleic acids.

A clinical 365bet娱乐book bed study for Ebola virus infection is currently in phase II.

MERS-infected mice performed much bette rwith this combination therapy, with reduced virus replication and improved lung function.

Function of Remdesivir  CAS NO: 1809249-37-3

Remdesivir, a nucleoside analogue with activity, has an EC50 value of 74 nM for sars-cov and mers-cov in HAE cells and 30 nM for mouse hepatitis virus in delayed brain tumor cells.

Recent studies have shown that Radixivir has a certain activity in inhibiting the new crown virus.

Application of Remdesivir CAS NO: 1809249-37-3

Remdesivir, a nucleoside analogue with antiviral activity, has an EC50 value of 74 nM for sars-cov and mers-cov in HAE cells and

30 nM for mouse hepatitis virus in delayed brain tumor cells.

Remdesivir    CAS NO: 1809249-37-3  Preparation:

 The second generation synthesis method introduced by Nature2016(Nature, 2016, Doi:10.1038/nature17180) can be amplified to the level of 100g in 6 steps in the laboratory, with yields of 40%,85%,86%,90%,70%,69%, respectively. The synthesis of intermediate 6 requires two steps, with yields of 80% and 39% of nucleoside triphosphate (NTP) in 28%.

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