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Name: Plerixafor   

CAS NO:155148-31-5

EINECS:N/A

MF: C28H62Cl8N8

MW: 830.500

MP: N/A

BP:657.5?C at 760mmHg

Density:0.962g/cm3

Appearance: Primrose yellow

Purity: 99% min

Package: 25g, 100g, 500g, bulk package 

Application: Pharmaceutical intermediate

Other name:

Bicyclam;

1,4,8,11-Tetraazacyclotetradecane, 1,1'-[1,4-phenylenebis(methylene)]bis-, hydrochloride, hydrate (1:8:2);

1,1'-[1,4-Phenylenebis-(methylene)]-bis-(1,4,8,11-tetraazacyclotetradecane)octahydrochloride;

Plerixafor octahydrochloride;

Plerixafor  CAS NO: 155148-31-5 is an immunostimulant used to mobilize hematopoietic stem cells in cancer patients into the bloodstream. The stem cells are then extracted from the blood and transplanted back to the patient. The drug was developed by AnorMED which was subsequently bought by Genzyme.

Function & Application:

A new drug called AMD3100 - also known as Plerixafor - could be used to help block the formation of the protein and break down the cancer's barrier.

The body's ‘T cells’ - which attack the cancerous cells - are then able to break through and fight the tumour.

Researchers had been testing the drug on mice but now feel it is ready to be tested on humans - with a cure potentially available within the next ten years.

Dr Douglas Fearon, from the research institute, has now claimed the breakthrough could be the first step towards a cure for many forms of the disease.

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