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Description of CAS 10465-78-8 N,N,N',N'-Tetramethylazodicarboxamide:

Diamide, also known as N,N,N′,N′-Tetramethylazodicarboxamide(TMAD)CAS NO: 10465-78-8 , is an organic compound . It is used as a thiol oxidizing agent and has been used to titrate protein glutathiolation to discriminate from other oxidative protein modifications . It is also used in the medical field to stimulate the release of insulin from pancreatic beta-cells, thereby lowering blood glucose

Application of CAS 10465-78-8 N,N,N',N'-Tetramethylazodicarboxamide:

TMAD CAS NO: 10465-78-8 is a synthetic compound that inhibits the enzyme caprylic acid acetyltransferase (CAT). It is also a biochemical sensor that responds to changes in the environment by changing its optical properties. TMAD can be used as a response element for salt metathesis, which is an important reaction in organic chemistry. The rate constant of the TMAD-catalyzed reaction has been determined and found to be 6.4e-4s-1. The gene for the protein ryanodine receptor (RyR) has been shown to be sensitive to TMAD and other compounds like diamide and anthranilic acid. Nuclear DNA has been shown to be damaged by TMAD, with cytosolic Ca2+ being increased. Fluorescence probe experiments have confirmed that TMAD binds to nuclear dna and cytosolic ca2+.

Future Directions
The future of Diamide CAS NO: 10465-78-8 chemistry involves addressing the issue of diamide resistance in some of the world's most destructive lepidopteran species, including populations of diamondback moth, tomato leafminer, rice stem borer, and more recently beet armyworm . The Insecticide Resistance Action Committee calls for effective diamide insecticide resistance management by following a three-step strategy of resistance identification, tracking, and prediction
 

Packaging of  CAS 10465-78-8 N,N,N',N'-Tetramethylazodicarboxamide:

 The usual one package of  CAS 10465-78-8 N,N,N',N'-Tetramethylazodicarboxamide is 25kg/drum. But we could also subpackage it according to our customers'requirements.Such as 1kg/bag, 5kg/bag, 10kg/bag,etc.

Generally, the powder of  CAS 10465-78-8 N,N,N',N'-Tetramethylazodicarboxamide will be packed in sealed plastic bags, and then be locked into the carton barrels or sealed in woven bags or craft paper bags. But we could also pack it with aluminium foil bags to provide more protection to the goods as our customers' required.

N,N,N',N'-Tetramethylazodicarboxamide   CAS NO: 10465-78-8 It's Non-toxic, odorless, non-flammable and soluble in alkali, insoluble in alcohol gasoline benzopyridine and water gas volume 230~250 ml/g.

N,N,N′,N′‐Tetramethylazodicarboxamide (TMAD) CAS NO: 10465-78-8. Also could as a  New Versatile Reagent for Mitsunobu Reaction.

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