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Name:L-Prolinamide

CAS NO: 7531-52-4

EINECS:231-397-0

MF: C5H10N2O

MW: 114.146

MP: 95-97&苍产蝉辫;°颁(濒颈迟.)

BP:303.6±31.0 °C at 760 mmHg

Density:1.1±0.1 g/cm3

Appearance: White powder

Purity: 99% min

Package: 25g, 100g, 500g, bulk package 

Application:Organic Intermediate

Other name:

2-Pyrrolidinecarboxamide, (S)-;

(2S)-2-Pyrrolidinecarboxamide;

(S)-Pyrrolidine-2-carboxylic acid amide;

(S)-pyrrolidine-2-carboxamide;

prolinamide CAS NO: 7531-52-4 is the intermediate of Vildagliptin, Vildagliptin (previously LAF237, trade names Galvus, Zomelis,) is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas. Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus.

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