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Name: Ivermectin   

CAS NO: 70288-86-7

Purity: 99%

MF: C48H74O14

MW:875.09

soluble: 4mg/L(temperature not stated)

Specific optical rotation: D +71.5 ± 3° (c = 0.755 in chloroform)

solubility: H2O: ≤1.0% KF

EINECS:274-536-0

Appearance: White to Off-white solid

Package: 25g, 100g, 500g, bulk package

Application:Pharmaceutical intermediate

Other name:

Vermic;

Ivosint;

Mectizan;

IVOMEC;

22,23-Dihydro-5-O-demethylavermectin A1a;

Avermectin A1a, 5-O-demethyl-22,23-dihydro-;

Ivermectin CAS NO: 70288-86-7 is a medication that is effective against many types of parasites. It is used to treat head lice,  scabies, river blindness,  strongyloidiasis, and lymphatic filariasis, among others. It can be either applied to the skin or taken by mouth.The eyes should be avoided.

Ivermectin CAS NO: 70288-86-7 is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.

Ivermectin CAS NO: 70288-86-7 for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.

Ivermectin CAS NO: 70288-86-7 has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorine ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.

Application for the Ivermectin  CAS NO: 70288-86-7

1. Ivermectin is the derivatives of abamectin. Ivermectin belongs to oral semisynthetic broad-spectrum drug resistant parasites.  

2. Ivermectin has effect for most of the various life cycle nematodes.  

3. Ivermectin has effect for the microfilaria of onchocerca volvulus,but it does not has effect for the adult onchocerca volvulus  

4. Ivermectin has effect for dung round worms that is only stay in intestinal tract  

5. Ivermectin has selective inhibition.  

6. Ivermectin can not go through the blood brain barrier of humanbeings

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