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Name:Icariin

CAS: 489-32-7

EINECS: 610-440-0

MF: C33H40O15

MW: 676.66

MP: 223-225 ºC

BP: 948.5±65.0 °C(Predicted)

Density: 1.55

storage temp: 2-8°C

Appearance: Light yellow powder

Purity: 97% min

Applications: Pharmaceutical intermediates

Package:1kg, 5kg,25kg,bulk package 

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Other name:

Epimedium herb Ext;

Epimedium P.E;Icariin, froM EpiMediuM davidii Franch;Icariin Min 90%;

EpiMediuM Leaf Extract, Icariin 10% by HPLC;

 

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Description:

 Icariin is one of the major flavonoids of the herb Epimedium, which has long been used in Tranditional Chinese Medicine to treat bone fracture and prevent osteoporosis. Research has shown that icariin should be an effective component for the bone-strengthening activity of the herb Epimedium, and one of the possible mechanisms for this activity is to stimulate the proliferation and enhance the osteogenic differentiation of marrow stromal cells. 

Icariin is reported to prevent and treat sexual dysfunction related diseases and improve the use of vasoconstriction. Icariin is used to prepare angiotensin converting enzyme inhibitor medicines, which can be used to treat hypertension-complicated coronary diseases.

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Application:

 

1.in the preparation of topical treatment to determine its effects on the improvement of cutaneous wound healing in rats.

2.to test its analgesic effects on lower back pain (LBP) in rats.

3.as a potential treatment in osteoporosis condition in rats.

4.to study its effects on palmitate (PA)-induced insulin resistance in skeletal muscle C2C12 myotubes as a neuroprotective agent to study its effects on amyloid-β (Aβ)-induced neuronal insulin resistance in human neuroblastoma SK-N-MC cells.

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