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Name: Glimepiride      

CAS: 93479-97-1

Purity: 97% min

MF: C24H34N4O5S

MW:490.616

BP:677.0±65.0 °C at 760 mmHg

Density:1.3±0.1 g/cm3

MP: 212.2-214.5&苍产蝉辫;°颁

EINECS: N/A

Appearance: White crystal solid

Package: 25g, 100g, 500g, bulk package

Application: Pharmaceutical intermediate

Other name:

amary;

Glimepiridum;

Endial;

Endocrine series drugs application of 99% Glimepiride CAS NO. 93479-97-1

Glimepiride is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Glimepiride belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your body's natural insulin.

Its use is contraindicated in patients with hypersensitivity to glimepiride or other sulfonylureas.    Side effects from taking glimepiride include gastrointestinal tract (GI) disturbances, occasional allergic reactions, and rarely blood production disorders including thrombocytopenia, leukopenia, and hemolytic anemia. In the initial weeks of treatment, the risk of hypoglycemia may be increased. Alcohol consumption and exposure to sunlight should be restricted because they can worsen side effects.

Introduction of Glimepiride CAS NO. 93479-97-1

Glimepiride is a medium- to long-acting sulfonylureaantidiabetic drug. Like all sulfonylureas, glimepiride acts as an insulin secretagogue. It lowers blood sugar by stimulating the release of insulin by pancreatic beta cells and by inducing increased activity of intracellular insulin receptors. Not all secondary sufonylureas have the same risks of hypoglycemia. Glibenclamide (glyburide) is associated with an incidence of hypoglycemia of up to 20 30%, compared to as low as 2% to 4% with glimepiride. Glibenclamide also interferes with the normal homeostatic suppression of insulin secretion in reaction to hypoglycemia, whereas glimepiride does not. Also, glibenclamide diminishes glucagon secretion in reaction to hypoglycemia, whereas glimepiride does not.

Function of Glimepiride CAS NO. 93479-97-1

Glimepiride (Glimer) is indicated to treat type 2 diabetes mellitus; its mode of action is to increase insulin production by the pancreas. It is not used for type 1 diabetes because in type 1 diabetes the pancreas is not able to produce insulin.Its use is contraindicated in patients with hypersensitivity to glimepiride or other sulfonylureas, and during pregnancy.

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