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Description of Diphenylphosphine oxide (DPPO) CAS：4559-70-0

Diphenylphosphine oxide (DPPO) CAS：4559-70-0 is a versatile organophosphorus compound that has been used in a variety of applications.

 

Diphenylphosphine oxide (DPPO) CAS 4559-70-0 is used to made triphenylphosphine, alkenyl phosphine, addition to alkyne, and Wittig-Horner reagents. Synthesis of diphenylphosphine Derivatives Ph2P(O)H coupled with aryl trifluoromesulfonate, phosphine oxide is reduced to obtain diphenylarylphosphine, which is a commonly used chiral ligand;

 

Diphenylphosphine oxide can be used as a coupling partner to prepare various organophosphorus compounds by cross-coupling reaction with aryl halides in the presence of Ni/Zn catalyst;

 

In the presence of transition metal catalyst, alkenyl diphenyl phosphine oxide is synthesized by hydrophosphine acylation of terminal alkynes;

 

Chiral ligands containing diphenylphosphine were synthesized by PD-catalyzed coupling reaction with aryl trifluoromesylate for asymmetric catalytic reactions.

 

Name: Diphenylphosphine oxide  

CAS NO: 4559-70-0

EINECS:625-671-2

MF: C12H11OP

MW: 202.19

MP: 56-57 °C(lit.)

BP:102-105 °C at 0.2 mmHg

Storage:Inert atmosphere,Room Temperature

Appearance: White Crystal

Purity: 97% min

Package: 25g, 100g, 500g, bulk package

Application:Pharmaceutical Intermediates

 

 

Other name:

DPPO;

oxo(diphenyl)phosphanium;

Phosphorane, diphenyl-, oxide;

Application of Diphenylphosphine oxide (DPPO) CAS：4559-70-0

 

DPPO is a useful intermediate in the synthesis of other organophosphorus compounds, and it has been used in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. DPPO is also used in the production of polymers, catalysts, and other materials. In addition, DPPO has been studied for its potential biological applications, including its use as a drug delivery system and its potential role in regulating gene expression.

Future Directions
Diphenylphosphine oxide has potential applications in the development of highly valuable phosphorus compounds . It can be transformed into three reactive organophosphorus intermediates that efficiently give the corresponding functional organophosphorus compounds in good yields.

 

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