+86-371-55052911
Language
+86-371-55052911
Language
CAS£º 749927-69-3
MF£º C8H7BrFNO
MW£º 232.05 g/mol
Appearance£º White to off-white solid
Made in China
Worldwide delivery
Introduction and application of CAS No. 749927-69-3 | 4-Bromo-2-fluoro-N-methylbenzamide
4-Bromo-2-fluoro-N-methylbenzamide is an impurity in the pharmaceutical drug nilutamide. It is a ligand that binds to the androgen receptor and inhibits the binding of dihydrotestosterone, reducing its effect on prostate cells. It has been shown to have pharmacokinetic properties similar to nilutamide, which is a drug used for treating prostate cancer. This impurity is also found in small quantities in other drugs including cyclobutanone, 2-aminoisobutyric acid, and chloral hydrate. The elucidation of these impurities can help regulate the quality of pharmaceutical drugs.
Synonyms:
N-METHYL 4-BROMO-2-FLUOROBENZAMIDE;
4-Bromo-2-fluoro-N-methyl-benzamide;
Benzamide, 4-bromo-2-fluoro-N-methyl-.
Specification of CAS No. 749927-69-3 | 4-Bromo-2-fluoro-N-methylbenzamide
|
ITEMS |
SPECIFICATION |
|
CAS |
749927-69-3 |
|
MF |
C8H7BrFNO |
|
MW |
232.05 g/mol |
|
Appearance |
White to off-white solid |
|
Melting point |
127¡æ |
|
Boiling Point |
284.8±30.0 °C at 760 mmHg |
|
Flashing point |
126.1±24.6 °C |
|
Density |
1.5±0.1 g/cm3 |
|
Refractive Index |
1.546 |
|
Vapour Pressure |
0.0±0.6 mmHg at 25°C |
|
Enthalpy of Vaporization |
52.4±3.0 kJ/mol |
|
Storage |
store at 10°C - 25°C, close container well, keep dry. |
|
Safety Information |
HS Code 2924299090 |
Package, transportation and application of CAS No. 749927-69-3 | 4-Bromo-2-fluoro-N-methylbenzamide
Package: 100g, 250g, 500g, 1kg, bulk packages
Transportation: by courier/ by air/ by sea
Application: Pharmaceutical intermediates
Hot Tags: cas no. 749927-69-3 | 4-bromo-2-fluoro-n-methylbenzamide, China, manufacturers, in stock, free sample, high quality, low price, CAS 503 40 2, 5 Chloro 1 Methylimidazole, CAS 182224 71 1, 1 nitro 2 propan 2 ylbenzene, CAS No 619 66 9, CAS 2243 56 3
