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CAS: 77-52-1 Ursolic Acid

CAS: 77-52-1 Ursolic Acid

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CAS: 77-52-1 Ursolic acid

Ursolic acid (UA) (3¦Â-hydroxy-urs-12-en-28-oic-acid) (Fig. 1) is a pentacyclic triterpenoid carboxylic compound (C30H48O3) which may occur in the free acid form or as aglycones for triterpenoid saponins. Its isomer, oleanolic acid (OA) (3¦Â-hydroxy-olea-12-en-28-oic-acid), presents different substitution of the methyl group, but they have similar molecular structures and pharmacological activity. Oleanolic acid and ursolic acid are ubiquitous triterpenoids in plant kingdom, medicinal herbs, and are integral part of the human diet, once they are found in fruits and medicinal herbs.


Figure 1 the chemical structure of Ursolic acid In recent years they became the subject of many publications because of their various activities and low toxicity. Many beneficial effects such as antioxidative, antimicrobial, anti-inflammatory, anticancer, anti-hyperlipidemic, analgesic, hepatoprotectory, gastroprotective, anti-ulcer, anti-HIV, cardiovascular, antiatherosclerotic and immunomodulatory effects have been reported. Several works have shown that the ursolic acid can also stimulate muscle growth, reduce fat gain and enhance the epidermal permeability barrier recovery in the skin, therefore it has been proposed as a skin therapeutic agent and it could be introduced in sport supplements, cosmetics and health products.

 

SPECIFICATION OF CAS: 77-52-1 Ursolic acid

ITEMS

SPECIFICATION

Melting point 

292 ¡ãC (dec.) (lit.)

alpha 

59 ? (c=0.3, pyridine)

storage temp. 

2-8¡ã°ä

Merck 

14,9890

color 

White to off-white

refractive index 

1.4940 (estimate)

form 

Crystalline Powder or Needles

Water Solubility 

insoluble

density 

1.0261 (rough estimate)

Boiling point 

502.79¡ãC (rough estimate)

pka

4.68¡À0.70(±Ê°ù±ð»å¾±³¦³Ù±ð»å)

EPA Substance Registry System

Urs-12-en-28-oic acid, 3-hydroxy-, (3.beta.)- (77-52-1)

BRN 

2228563

CAS DataBase Reference

77-52-1(CAS DataBase Reference)

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