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Molecular Formula: C30H48O3
Molecular Weight: 456.71
Purity: 97% Min.
Package: 250 mg / 1 g / 5 g
Worldwide Delivery
Betulinic Acid is a natural pentacyclic triterpenoid. Betulinic Acid displays anti-inflammatory and anti-HIV activity. Betulinic Acid selectively induces apoptosis in tumor cells by directly activati ng the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. Betulinic Acid also exhibits TGR5 agonist activity
This compound is a pentacyclic triterpene obtained from Betula and Zizyphus species,which shows selective cytotoxicity against human melanoma cells (Shoeb2006). It generates reactive oxygen species, activates MAPK cascade, inhibitstopoisomerase I, inhibits angiogenesis, modulates pro-growth transcriptionalactivators, modulates the activity of aminopeptidase-N, and thereby inducesapoptosis in cancer cells.
SPECIFICATION OF CAS: 472-15-1 Betulinic acid
ITEMS | SPECIFICATION |
Melting point | 295-298 ¡ãC (dec.) (lit.) |
InChIKey | QGJZLNKBHJESQX-FZFNOLFKSA-N |
alpha | D25 +7.5¡ã (c = 0.37 in pyridine) |
storage temp. | 2-8¡ã°ä |
Merck | 14,1190 |
refractive index | 7.8 ¡ã (C=0.9, Pyridine) |
form | neat |
density | 1.065 g/cm3 |
Boiling point | 550.0 ¡ãC |
pka | 4.61 |
optical activity | [¦Á]20/D +7.8¡ã, c = 0.9 in pyridine |
CAS DataBase Reference | 472-15-1(CAS DataBase Reference) |
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