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Molecular Formula: C22H16F4N4OS
Molecular Weight: 460.45
Purity: 97% Min.
Package: 1 g / 5 g / 25 g
Worldwide Delivery
In stock
Introduction
ULK-101 is an effective and selective ULK1 inhibitor with IC50 values of 8.3 nM and 30 nM for ULK1 and ULK2, respectively.
| Target | Value |
| ULK1 (Cell-free assay) | 8.3 nM |
| ULK2 (Cell-free assay) | 30 nM |
In vitro studies£º
ULK-101 inhibits the induction of autophagy and autophagy flux under different stimuli. ULK-101 sensitizes lung cancer cells carrying KRAS mutations to nutrient stress.
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