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Name: 3-Methylquinoline-8-sulfonyl chloride   

CAS NO: 74863-82-4

Purity: 99% min

MF: C10H8ClNO2S

MW:241.694

BP:371.5±27.0 °C at 760 mmHg

Density:1.4±0.1 g/cm3

MP: 158-159?C

EINECS:N/A

Appearance: Off-White to Pale Brown Solid

Package: 25g, 100g, 500g, bulk package 

Application:Pharmaceutical Intermediates

Other name:

3-Methyl-8-quinolinesulfonyl chloride;

8-Quinolinesulfonyl chloride, 3-methyl-;

Method for synthesizing 3-methylquinoline-8-sulfonyl chloride  CAS NO: 74863-82-4

The method comprises the steps: with aniline as a starting material, carrying out a reaction with propionic acid to obtain N-phenylpropionamide, then generating a ring to obtain 2-chloro-3-methylquinoline, next carrying out halogenated hydrocarbon reduction to obtain 3-methylquinoline, and finally carrying out chlorosulfonation to obtain the product 3-methylquinoline-8-sulfonyl chloride. The method is low in cost, simple in operation, good in economic benefits, high in yield, and suitable for industrialized production. With the method of the invention, 3-methylquinoline-8-sulfonyl chloride can be obtained with high yield rate.

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