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Description of 3-Amino-2-pyrazinecarboxylic Acid CAS NO: 5424-01-1

 

Name: 3-Amino-2-pyrazinecarboxylic Acid   

CAS NO: 5424-01-1

Purity: 98% min

MF: C5H5N3O2

MW:139.11

BP:401.3±45.0 °C at 760 mmHg

Density:1.5±0.1 g/cm3

MP: 205-210 °C (dec.)(lit.)

EINECS: 226-558-7

Appearance: Crystalline Powder

Package: 25g, 100g, 500g, bulk package 

Application:Pharmaceutical Intermediates

 

Other name:

3-amino-2-carboxy-pyrazine;

3-amino-pyrazine-2-carboxylic acid;

3-Aminophrazine-2-carboxylic acid;

2-Pyrazinecarboxylic acid, 3-amino-;

3-Aminopyrazinoic acid;

2-aminopyrazine-3-carboxylic acid;

2-Amino-3-pyrazinecarboxylic Acid;

 

1.3-Amino-2-pyrazinecarboxylic acid (APC)CAS NO: 5424-01-1 is a molecule that has been studied from many different theoretical perspectives. It has been shown to have magnetic, vibrational and spectroscopic properties. APC has a molecular electrostatic potential that can be calculated by the functional theory of atoms in molecules.

 

2.3-Amino-2-pyrazinecarboxylic Acid  CAS NO: 5424-01-1 could used as intermediate in organic synthesis or as an intermediate of amclopyrazole, a diuretic.

 

Application of 3-Amino-2-pyrazinecarboxylic Acid CAS NO: 5424-01-1

 

1.Synthesis of Favipiravir for COVID-19 Treatment
Summary of Application: Favipiravir is a wide-spectrum antiviral generic drug that has received large attention during the recent COVID-19 pandemic. 3-Aminopyrazine-2-carboxylic acid is used in the synthesis of Favipiravir .
Methods of Application: The synthesis of Favipiravir involves the use of 3-Aminopyrazine-2-carboxylic acid to obtain the 3,6-dichloropyrazine-2-carbonitrile intermediate. This intermediate is then subjected to fluorination, hydroxylation, and nitrile hydrolysis reactions to afford Favipiravir.

 

2. Anticancer Activity of Transition Metal Complexes

 

3. Synthesis of Antimicrobial Derivatives
Summary of Application: 3-Aminopyrazine-2-carboxylic acid is used to synthesize a series of N-substituted 3-aminopyrazine-2-carboxamides with free amino groups in position 3 on the pyrazine ring

 

4.Synthesis of Iron (III) Complexes
Summary of Application: 3-Aminopyrazine-2-carboxylic acid is used to synthesize mono-, di-, and polynuclear iron (III) complexes

5. Synthesis of Coelenterazine
Summary of Application: 3-Aminopyrazine-2-carboxylic acid is used in the synthesis of Coelenterazine, a substrate for the marine bioluminescence system

6.Synthesis of Transition Metal Complexes for Anticancer Activity
Summary of Application: 3-Aminopyrazine-2-carboxylic acid is used to synthesize transition metal complexes that display significant anticancer activity .

 

 

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