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Microsomal biotransformation of benzo[ghi]perylene CAS NO: 191-24-2, a mutagenic polycyclic aromatic hydrocarbon without a "classic" bay region.

Carcinogenic polycyclic aromatic hydrocarbons (PAH), e.g., benzo[a]pyrene (BaP), possess a bay region comprising an ortho-fused benzene ring. Benzo[ghi]perylene (BghiP)  CAS NO: 191-24-2 represents the group of PAHs lacking such a "classic" bay region and hence cannot be metabolically converted like BaP to bay region dihydrodiol epoxides considered as ultimate mutagenic and carcinogenic metabolites of PAH. 

Name:Benzo[ghi]perylene    

CAS NO: 191-24-2

EINECS:205-883-8

MF: C22H12

MW: 276.33

MP: 277-279?C(lit.)

BP:501.0±0.0 °C at 760 mmHg

Density:1.4±0.1 g/cm3

Appearance: White powder

Purity: 99% min

Package: 25g, 100g, 500g, bulk package

Application:Organic intermediates

MBenzo[g,h,i]perylene CAS NO: 191-24-2 is a polycyclic aromatic hydrocarbon that can be found in wastewater and has been detected in the environment. It is an important chemical substance because it can cause DNA damage and inhibit enzyme activities. Benzo[g,h,i]perylene is used as an analytical tool to measure the matrix effect of wastewater samples. The matrix effect describes how substances in the sample affect the measurement of other substances. The optimum concentration for benzo[g,h,i]perylene is between 1-5 ?M for DNA binding activity and 10 ?M for transfer reactions. Synchronous fluorescence measurements are typically performed at a wavelength of 360 nm with an excitation wavelength of 340 nm. Synchrotron radiation (SR) is a type of high-energy X-ray radiation that has a wide range of uses in science and industry. SR provides intense beams of light to probe materials that cannot be studied using conventional light sources such.

Benzo[ghi]perylene (B[ghi]P) CAS NO: 191-24-2 is a polycyclic aromatic hydrocarbon (PAH) that is found in the environment. It is a component of diesel exhaust, cigarette smoke, and other sources of air pollution. B[ghi]P has been linked to numerous health issues, including respiratory diseases, cancer, and reproductive problems.

Other name:

1,12-Benzperylene;

Benzo-1,12-perylene;

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