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Name:m-carborane
Other name: 5-Bromo-2-hydroxy-3-methylbenzoic acid;
2¦Ë2,3¦Ë2,4¦Ë2,5¦Ë2,6¦Ë2,7¦Ë2,8¦Ë2,9¦Ë2,11¦Ë2,12¦Ë2-»å±ð³¦²¹²ú´Ç°ù²¹²ú¾±³¦²â³¦±ô´Ç°Ú8.1.1±Õ
dodecane1,7-DICARBADODECARBORANE;
1,7-Dicarba-closo-dodecaboran;
1,7-Dicarba-closo-dodecaborane;
Name:m-carborane
Other name: 5-Bromo-2-hydroxy-3-methylbenzoic acid;
2¦Ë2,3¦Ë2,4¦Ë2,5¦Ë2,6¦Ë2,7¦Ë2,8¦Ë2,9¦Ë2,11¦Ë2,12¦Ë2-»å±ð³¦²¹²ú´Ç°ù²¹²ú¾±³¦²â³¦±ô´Ç°Ú8.1.1±Õ
dodecane1,7-DICARBADODECARBORANE;
1,7-Dicarba-closo-dodecaboran;
1,7-Dicarba-closo-dodecaborane;
1,7-Dicarbadodecaboran;
1,7-Dicarbadodecaboran;
CAS: 16986-24-6
EINECS: 241-065-7
MF: C2H12B10
MW: 144.22700
MP: 272 ¡ãC
Appearance: White crystal powder
Purity: 97% min
Package: 25g, 100g, 500g, bulk package
A series of m-carborane CAS: 16986-24-6 derivatives was prepared based upon the structures of antiestrogenic drugs and their activities were evaluated by estrogen receptor alpha (ER¦Á) binding assay and transactivation assay using human breast cancer cell line, MCF-7 cells. The m-carborane CAS: 16986-24-6 bisphenol 5 exhibited about a thousand times more potent ER agonistic activity than the o-carborane bisphenol 11. The m-carborane CAS: 16986-24-6 bisphenol structure appears to be a favorable hydrophobic pharmacophore for the development of novel selective estrogen receptor modulators.
New polybenzimidazoles (PBIs) containing the m-carborane CAS: 16986-24-6 ring have been obtained by chemical cyclization of m-carborane CAS: 16986-24-6 containing polyaminoamides (PAAs), using a complex of N-methyl-2-pyrrolidine with sulphur trioxide, and polyphosphoric acid esters as cyclodehydrating agents.
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