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Polidocanol is a local anaesthetic and antipruritic component of ointments and bath additives. It relieves itching caused by eczema and dry skin. It is formed by the ethoxylation of dodecanol.

The substance is also used as a sclerosant, an irritant injected to treat varicose veins, under the trade names Asclera, Aethoxysklerol and Varithena. Polidocanol causes fibrosis inside varicose veins, occluding the lumen of the vessel, and reducing the appearance of the varicosity.

The FDA has approved polidocanol injections for the treatment of small varicose (less than 1mm in diameter) and reticular veins (1 to 3mm in diameter). Polidocanol works by damaging the cell lining of blood vessels, causing them to close and eventually be replaced by other types of tissue.

Pure polidocanol for pharmaceutical use

Product Details:      

Name: Polyoxyethylene lauryl ether

Synonyms:

yx500;

AEO4;

depeg;

la7;

g3711;

ped;

bl9;

do9;

g3707;

polyoxethyleneglycol-23 lauryl ether;

bl9ex;

Polidocanol (PEG Monododecyl Ether);

CAS: 9002-92-0

EINECS: 500-002-6

MF: C58H118O24

MW: 1199.54000

MP: 41-45 °C(lit.)

BP: 100 °C(lit.)

FP: >230 °F

Purity: 95%min

Density: 0.99 g/mL±0.002 g/mL at 20 °C

Refractive index: n20/D 1.461

Storage condition: Store at RT.

Appearance: White to yellowish paste

Stability: Stable. Combustible. Incompatible with strong oxidizing agents.

Package: 5g, 25g, 100g, 500g, 1kg, 25kg

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