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Name:Methoxycarbonyl-L-tert-leucine
CAS:162537-11-3
MF:C8H15NO4
MW:189.21
EINECS:1308068-626-2
Name:Methoxycarbonyl-L-tert-leucine
CAS:162537-11-3
MF:C8H15NO4
MW:189.21
EINECS:1308068-626-2
²Ñ±Ê:109¡ã°ä
BP:320.9¡À25.0 ¡ãC
FP:147.9¡À23.2 ¡ãC
Density:1.126¡À0.06 g/cm3
Appearance:White powder
Purity:97%
Solubility:Soluble in ethyl acetate and methanol
Storage temp:2-8¡ãC
Applications: Pharmaceutical intermediates
Package:5g, 10g,100g,bulk package
Other name:
(S) -2-Methoxycarbonylamino-3,3-dimethylbutyric acid;
Methoxycarbonyl-L-tert-leucine;
N-(Methoxycarbonyl)-3-methyl-L-valine;Atazanavir related coMpound A;
Application:
The coupling of the two key intermediates, N-(methoxycarbonyl)-l-tert-leucine acylated benzyl hydrazine and chloromethyl ketone, via an S N 2 reaction furnished the amino ketone in high yield under our optimized conditions in practical synthesis of the HIV Protease Inhibitor Atazanavir via a Highly diastereoselective Reduction Approach.
Definition:
Methoxycarbonyl-L-tert-leucine is a kind of amino acid deriviative. It is a very useful intermediate for efficient synthesis of the HIV protease inhibitor BMS-232632 as well as atazanavir bisulfate.
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