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Methoxycarbonyl-L-tert-leucine CAS:162537-11-3

Methoxycarbonyl-L-tert-leucine CAS:162537-11-3

Name:Methoxycarbonyl-L-tert-leucine
CAS:162537-11-3
MF:C8H15NO4
MW:189.21
EINECS:1308068-626-2

Name:Methoxycarbonyl-L-tert-leucine

CAS:162537-11-3

MF:C8H15NO4

MW:189.21

EINECS:1308068-626-2

²Ñ±Ê:109¡ã°ä

BP:320.9¡À25.0 ¡ãC

FP:147.9¡À23.2 ¡ãC

Density:1.126¡À0.06 g/cm3

 



Appearance:White powder

Purity:97%

Solubility:Soluble in ethyl acetate and methanol

Storage temp:2-8¡ãC

Applications: Pharmaceutical intermediates

Package:5g, 10g,100g,bulk package



Other name:

(S) -2-Methoxycarbonylamino-3,3-dimethylbutyric acid;

Methoxycarbonyl-L-tert-leucine;

N-(Methoxycarbonyl)-3-methyl-L-valine;Atazanavir related coMpound A;

 



Application:

The coupling of the two key intermediates, N-(methoxycarbonyl)-l-tert-leucine acylated benzyl hydrazine and chloromethyl ketone, via an S N 2 reaction furnished the amino ketone in high yield under our optimized conditions in practical synthesis of the HIV Protease Inhibitor Atazanavir via a Highly diastereoselective Reduction Approach.


 

Definition:

Methoxycarbonyl-L-tert-leucine is a kind of amino acid deriviative. It is a very useful intermediate for efficient synthesis of the HIV protease inhibitor BMS-232632 as well as atazanavir bisulfate.

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