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Production Introduction

Name:Fmoc-D-leucine

CAS: 114360-54-2

MF: C21H23NO4

MW: 353.41

Density:1.2±0.1 g/cm3

Solubility:Insoluble in water

Appearance: White powder

Purity:97%

Storage temp:2-8°C

Applications:amino acid

Package:1g, 5g,25g,bulk package

Application:

A convergent synthesis of the proposed structure of (+)-pestalazine B has been achieved in 4 steps using the N-alkylation of an unprotected tryptophan diketopiperazine with a 3a-bromopyrrolidinoindoline where the condensation between L-tryptophan methyl ester and N-Fmoc-D-leucine in the presence of EDC as coupling agent afforded the corresponding L-Trp-D-Leu dipeptide.

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