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Description of 4,4'-Bis(hydroxymethyl)-2,2-bipyridine CAS NO:109073-77-0

 

Name:4,4'-Bis(hydroxymethyl)-2,2'-bipyridine

 

Other name:

2,2'-Bipyridine-4,4'-diyldimethanol;

4,4'-Bis(hydroxymethyl)-2,2'-bipyridyl;

[2,2'-Bipyridine]-4,4'-diyldimethanol;

[2-[4-(hydroxymethyl)pyridin-2-yl]pyridin-4-yl]methanol;

 

CAS: 109073-77-0

MF: C12H12N2O2

MW: 216.24

MP: 170.6-171.4 °C

BP:450.4±40.0 °C(Predicted)

Density:1.281±0.06 g/cm3(Predicted)

Appearance: off-white powder

Purity: 97% min

Package: 25g, 100g, 500g, bulk package 

Storage:Keep in dark place,Sealed in dry,Room Temperature

 

 

Application of 4,4'-Bis(hydroxymethyl)-2,2-bipyridine CAS NO:109073-77-0

 

4,4'-Bis(hydroxymethyl)-2,2-bipyridine CAS NO:109073-77-0 is a replication inhibitor that has been used in the treatment of cancer. It has also been shown to be effective in the treatment of metabolic disorders and chronic bronchitis. 4,4'-Bis(hydroxymethyl)-2,2-bipyridine binds to the active site of human HMG-CoA reductase, which is an enzyme involved in cholesterol synthesis. This binding prevents the formation of HMG-CoA, preventing the conversion of acetyl coenzyme A into cholesterol. The drug also binds to microbial metabolism enzymes such as fatty acid synthase and alkanoic acid oxidoreductases and has significant cytotoxicity.

Chemistry: Used as a ligand in coordination chemistry to form metal complexes with unique properties.

Biology: Investigated for its potential as a building block in the synthesis of biologically active molecules.

Medicine: Explored for its potential use in drug design and development, particularly in the synthesis of compounds with therapeutic properties.

Industry: Utilized in the development of advanced materials, such as polymers and catalysts, due to its ability to form stable complexes with metals.

 

 

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