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Name:(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
CAS NO: 1006376-60-8
Purity: 99%
MF: C8H7ClF2O
MW: 192.5903864
BP: 256.3¡À35.0 ¡ãC
Name:(1S)-2-chloro-1-(3,4-difluorophenyl)-1-ethanol
CAS NO: 1006376-60-8
Purity: 99%
MF: C8H7ClF2O
MW: 192.5903864
BP: 256.3¡À35.0 ¡ãC
Density: 1.372¡À0.06 g/cm3
MP: N/A
EINECS: N/A
Appearance: Colorless Transparent Liquid
Package: 25g, 100g, 500g, bulk package
Application: 365betÓéÀÖ intermediate
Other name:
(Chloromethyl)-3,4-difluorobenzenemethanol;
(1S)-1-(3,4-Difluorophenyl)-2-chloroethanol;
(S)-2-Chloro-1-(3,4-difluoro-phenyl)-ethanol;
(1S)-2-chloro-1-(3, 4-difluorophenyl) ethanol ((S)- CFPL) CAS NO: 1006376-60-8 is an intermediate for the drug ticagrelor, and is manufactured via chemical approaches. To develop a biocata- lytic solution to (S)-CFPL, an inventory of ketoreductases from Chryseobacterium sp. CA49 were rescreened, and ChKRED20 was found to catalyze the reduction of the ketone precursor with excellent stereoselectivity (>99 % ee).
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