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Name:Lucigenin

Other name: Lucigenin nitrate;

Bis(N-methylacridinium) Nitrate;

10,10'-Dimethyl-9,9'-biacridinium dinitrate;

N,N`-dimethyl-9,9`-biacridinium dinitrate;

Dinitrate de 10,10'-diméthyl-9,9'-biacridinium;

9,9'-Bis(N-methylacridinium nitrate);

10,10'-Dimethyl-9,9'-biacridiniumdinitrat;

bis-n-methylacridinium nitrate;

10-methyl-9-(10-methylacridin-10-ium-9-yl)acridin-10-ium dinitrate;

9,9'-Biacridinium, 10,10'-dimethyl-, nitrate (1:2);

CAS: 2315-97-1

EINECS: 219-023-4

MF: C28H22N4O6

MW: 510.497

MP: 250?C

Appearance: Dark Yellow Powder

Purity: 97% min

Package: 25g, 100g, 500g, bulk package 

Catalase and the metabolic inhibitor, sodium azide, which inhibits the enzyme myeloperoxidase, had no inhibitory effect on Lucigenin  CAS: 2315-97-1

-dependent chemiluminescence production. Only the antioxidant, superoxide dismutase, prevented Lucigenin CAS: 2315-97-1 dependent chemiluminescence, indicating that this assay measures the production of superoxide anions by chondrocytes.

Electrochemically generated chemiluminescence of Lucigenin CAS: 2315-97-1.

The electrochemical reduction of Lucigenin CAS: 2315-97-1 has been shown to lead to dimethylbiacridene (DBA) as the product. The nonaqueous ECL has been shown to arise from reaction of superoxide with Lucigenin CAS: 2315-97-1. The spectral characteristics of the ECL, when compared with the fluorescence spectra and quantum efficiencies of NMA, DBA, and Lucigenin CAS: 2315-97-1, allow identification of the emitting species. NMA is the primary emitter formed in the excited state by the reaction of superoxide with Lucigenin CAS: 2315-97-1.

Lucigenin CAS: 2315-97-1 is most noted for its wide use as a chemiluminescent detector of superoxide anion radical (O2-.) production by biological systems.

Lucigenin CAS: 2315-97-1 (LC2+) is frequently used as a superoxide probe. To detect superoxide, Lucigenin CAS: 2315-97-1 must be reduced to the lucigenin cation radical (LC.+).

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