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Name:Ethyl 6-chloronicotinate

CAS:49608-01-7

MF:C8H8ClNO2

MW:185.61

EINECS:610-463-6

MP:26-30 °C

BP:98 °C

FP:104.5±21.8 °C

Density:1.245±0.06 g/cm3

Appearance:White to light yellow solid or colorless to yellow liquid

Purity:97%

Solubility:Chloroform (Slightly), Methanol (Slightly)

Storage temp:Inert atmosphere,Room Temperature

Package:5g, 10g,100g,bulk package

Other name:

3-Pyridinecarboxylic acid, 6-chloro-, ethyl ester;

ETHYL 6-CHLORONICOTINATE[FOR TAZAROTENE];

ETHYL 2-CHLOROPYRIDINE-5-CARBOXYLATE;

Ethyl 6-chloronicoti;

2-Chloro-5-pyridinecarboxylicacid ethylester;

Ethyl 2-chloropyridine-3-carboxylate, 6-Chloronicotinic acid ethyl ester;

Application:

Ethyl 6-chloronicotinate is a nicotinic acid derivative used in the preparation of potent H3 receptor antagonists.

Description:

Ethyl 6-chloropyridine-3-carboxylate (Ethyl-6-chloronicotinate, E-6-ClN) undergoes direct amidation on reacting with benzylamine in the presence lanthanum trifluoromethanesulfonate La(OTf)3. The structural and physicochemical properties of E-6-ClN have been investigated based on its spectroscopic data, time-dependent density functional theory and density of state diagrams.

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