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Name:ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate

CAS:161797-99-5

MF:C13H13NO3S

MW:263.31

EINECS:605-268-8

MP:180 ?C

BP:426.8±55.0 °C

FP: 211.9±31.5 °C

Density:1.274

 

Appearance:White Solid

Purity:97%

Solubility:DMSO (Slightly), Methanol (Very Slightly)

Storage temp:Sealed in dry,Room Temperature

Package:5g, 10g,100g,bulk package

Other name:

ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate;

Ethyl 2-(4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate;

2-(4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylicacid ethyl ester;

2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate;

 

Application:

Ethyl 2-(4-Hydroxyphenyl)-4-methylthiazole-5-carboxylate is used in the synthesis of the major metabolites of Febuxostat, a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.

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