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Name:Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

CAS:160844-75-7

MF:C18H20N2O3S

MW:344.43

EINECS:927-913-5

MP:176 °C

BP:497.1±55.0 °C

FP:N/A?

Density:1.22

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Appearance:?White solid

Purity:97%

Solubility:DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)

Storage temp:Sealed in dry,Room Temperature

Package:5g, 10g,100g,bulk package

Other?name:

5-Thiazolecarboxylicacid, 2-[3-cyano-4-(2-Methylpropoxy)phenyl]-4-Methyl-, ethyl ester;

2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate;

ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl;

Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate;

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Application:

Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.

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